The Dynamics Data Engine Powering Predictive BioAI

Biology has a
token problem.

LLMs took off when the right data achieved scale: trillions of tokens. BioAI is lagging because no one has defined the fundamental tokens for living systems — until now. Base4 generates at scale the foundational data needed to drive a throughline from molecules to a full human model.

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15+ yrs
Dynamics research and
pharma partnerships
300k×
Expansion in available
molecular behavior data
20k×
Faster than classical quantum
mechanical calculations
Proprietary
Novel dynamics data unavailable anywhere else
Physics Grounded
Atomic level foundation captures quantum properties
Combinatorial
Fragmentation enables combinatorial tokens
Compounding
Modularity allows for exponential data set growth
We built the atomic layer

Atomic Tokens:
Fundamental units of the molecular language

Every biological process happens at the atomic level. We built a data factory that generates Atomic Tokens at scale: physics-grounded, time-resolved data capturing how each atom behaves. This is the data layer biology has been missing and is the foundational unit to tie together multiple scales of the living system.

The Atomic Foundation is Being Laid Now

Enabling a throughline to virtual cells...
and eventually a complete human model.

Atomic Tokens are the data that make foundation models for living systems possible. Now, AI can learn how molecules behave, interact, and respond, building predictive insights across novel biological pathways, drug discovery, disease understanding, synthetic biology, foundation modeling ... the limits are unknown.

Disease Modeling
Understand the molecular effects and pathological drivers at the atomic level.
Drug Discovery
Predict how any biomolecule and drug will behave, engage and interact.
Foundation Model Training
Train AI with the atomic data it needs to reason about biology.
The Team

Built by people who've
lived inside the problem.

Entrepreneurs and scientists who spent 15+ years resolving the dynamics of biology.

Joshua Fairbank
Joshua Fairbank
CEO
Previously —
Co-founder of Akebia (IPO) and Aerpio (IPO). Adjunct Professor of Deep Tech @ UChicago. Chicago Booth MBA.
Hashim Al-Hashimi
Hashim Al-Hashimi, PhD
Platform Architect
Previously —
Vagelos Professor of Biochemistry & Molecular Biophysics @ Columbia. Yale PhD Biophysical Chemistry. 12,000+ citations.
Isaac Kimsey
Isaac Kimsey, PhD
Engine & AI
Previously —
AI development lead. Multiple pharma R&D partnerships. Duke PhD Biochemistry. 2× Nature author on RNA dynamics.
Yang Zheng
Yang Zheng
BD & Operations
Previously —
Co-founder of MicroQuin & Oxalo. Secured multi-million dollar pharma partnerships. Chicago Booth MBA.
Get in touch

Reach out.

We're in conversations with foundation model labs, pharma and biotechs, academic researchers, and a small number of aligned investors. If that sounds like you, reach out.

We read everything.